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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K6
All Species:
23.33
Human Site:
Y290
Identified Species:
64.17
UniProt:
O95382
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95382
NP_004663.3
1288
142596
Y290
S
Y
R
D
V
Q
D
Y
S
A
I
I
E
L
V
Chimpanzee
Pan troglodytes
XP_513244
1288
142617
Y290
S
Y
R
D
V
Q
D
Y
S
A
I
I
E
L
V
Rhesus Macaque
Macaca mulatta
XP_001111127
1297
143635
Y290
S
Y
R
D
V
Q
D
Y
S
A
I
I
E
L
V
Dog
Lupus familis
XP_544471
1476
162831
Y470
S
Y
R
D
V
Q
D
Y
S
A
I
I
E
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTR2
1291
143036
Y291
S
Y
R
D
V
Q
D
Y
S
A
I
I
E
L
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511920
1243
141469
T278
L
D
S
N
F
S
D
T
E
S
R
D
H
G
A
Chicken
Gallus gallus
XP_419725
1260
143069
M261
R
Q
K
A
L
E
I
M
I
P
L
V
E
Q
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001155222
1364
153160
Y314
S
Y
R
D
I
Q
D
Y
E
S
I
V
K
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202919
1288
145042
L263
L
H
L
Y
A
F
A
L
N
R
R
K
K
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.2
77.9
N.A.
87
N.A.
N.A.
46.5
46.4
N.A.
44.5
N.A.
N.A.
N.A.
N.A.
39.4
Protein Similarity:
100
99.6
97.1
81
N.A.
91
N.A.
N.A.
62.8
63
N.A.
61.5
N.A.
N.A.
N.A.
N.A.
56.2
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
6.6
6.6
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
20
40
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
12
0
12
0
0
56
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
67
0
0
78
0
0
0
0
12
0
0
0
% D
% Glu:
0
0
0
0
0
12
0
0
23
0
0
0
67
0
12
% E
% Phe:
0
0
0
0
12
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% G
% His:
0
12
0
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
12
0
12
0
12
0
67
56
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
0
0
0
12
23
0
0
% K
% Leu:
23
0
12
0
12
0
0
12
0
0
12
0
0
67
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
12
0
0
0
12
0
% P
% Gln:
0
12
0
0
0
67
0
0
0
0
0
0
0
12
0
% Q
% Arg:
12
0
67
0
0
0
0
0
0
12
23
0
0
0
0
% R
% Ser:
67
0
12
0
0
12
0
0
56
23
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
56
0
0
0
0
0
0
23
0
0
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
67
0
12
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _